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Why Do Many Adults Wake Up with a Damp Pillow? Exploring 8 Common Reasons for Nighttime Drooling

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5. Excess Saliva Production (Hypersalivation)

When the Body Produces Too Much Saliva

Some adults naturally produce more saliva, especially at night.

Possible triggers include:

  • Acid reflux (GERD)
  • Certain foods eaten before bed
  • Medications
  • Dental issues

The body may increase saliva production as a protective response—particularly in acid reflux, where saliva helps neutralize stomach acid.

If too much saliva is produced and swallowing slows during sleep, drooling becomes more likely.


6. Medications and Their Side Effects

Drugs That Can Increase Drooling

Several medications list drooling or excess saliva as a side effect, including:

  • Certain antidepressants
  • Antipsychotics
  • Sedatives and sleeping pills
  • Medications affecting the nervous system

These medications may:

  • Relax facial muscles
  • Reduce swallowing frequency
  • Increase saliva production

If drooling started after beginning a new medication, this may be the cause.


7. Jaw, Dental, or Oral Structure Issues

Structural Factors That Affect Saliva Control

Certain anatomical features can make drooling more likely:

  • Misaligned teeth
  • Overbite or underbite
  • Weak lip seal
  • Jaw tension or TMJ disorders

If the lips don’t close fully or the jaw relaxes unevenly during sleep, saliva may escape more easily.

Dental appliances such as retainers or night guards can also temporarily increase drooling while the mouth adapts.

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